(2E)-3-(3,4-DIMETHOXYPHENYL)ACRYLIC ACID - Names and Identifiers
(2E)-3-(3,4-DIMETHOXYPHENYL)ACRYLIC ACID - Physico-chemical Properties
Molecular Formula | C11H12O4
|
Molar Mass | 208.21 |
Density | 1.203 |
Melting Point | 181-183 °C(lit.) |
Boling Point | 367.4±27.0 °C(Predicted) |
pKa | 4.53±0.10(Predicted) |
(2E)-3-(3,4-DIMETHOXYPHENYL)ACRYLIC ACID - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
WGK Germany | 3 |
(2E)-3-(3,4-DIMETHOXYPHENYL)ACRYLIC ACID - Upstream Downstream Industry
(2E)-3-(3,4-DIMETHOXYPHENYL)ACRYLIC ACID - Introduction
(E)-3-(3,4-Dimethoxyphenyl)acrylic acid, the chemical formula is C11H12O4. It is an organic compound with the appearance of a white crystalline solid. The following is an introduction to the nature, use, preparation and safety information of (E)-3-(3,4-dimethoxyphenyl) acrylic acid:
Nature:
-Solubility:(E)-3-(3,4-Dimethoxyphenyl)acrylic acid is soluble in organic solvents such as ethanol, methanol and chloroform, and slightly soluble in water.
-Melting point: about 150-154 degrees Celsius.
-Chemical properties:(E)-3-(3,4-Dimethoxyphenyl)acrylic acid is an optically active organic acid, which has a crystallization transition point of colorless to yellow liquid. It exhibits acylation reactions with multiple compounds.
Use:
-Chemical research:(E)-3-(3,4-Dimethoxyphenyl)acrylic acid can be used as an important raw material for organic synthesis.
-Antioxidant: Due to its strong antioxidant activity against oxygen and free radicals,(E)-3-(3,4-dimethoxyphenyl) acrylic acid is used to protect lipids in food and cosmetics from oxidation damage.
-Drug development:(E)-3-(3,4-dimethoxyphenyl) acrylic acid is also used in the research and development of anti-inflammatory, anti-tumor and anti-mosquito bite drugs.
Preparation Method:
(E)-3-(3,4-dimethoxyphenyl) acrylic acid has many preparation methods. The following is one of the common methods:
1. p-methoxybenzoic acid and acetic anhydride are esterified to obtain p-methoxyphenylethyl acetate.
2. p-methoxyphenylacetic acid is generated by alkaline hydrolysis of p-methoxyphenylethyl acetate.
3. p-methoxyphenylacetic acid and phenylacetylene are reacted in organic synthesis to obtain (E)-3-(3,4-dimethoxyphenyl) acrylic acid.
Safety Information:
- (E)-3-(3,4-Dimethoxyphenyl)acrylic acid is chemically a low-toxic substance, but it is still necessary to pay attention to safe operation.
-Undissolved (E)-3-(3,4-Dimethoxyphenyl)acrylic acid Avoid direct contact with skin and eyes, and make sure to operate in a well-ventilated place.
-Wear personal protective equipment such as gloves, goggles and laboratory clothing when in use.
-If ingested or inhaled, seek medical attention and bring the chemical safety data sheet for the compound.
Last Update:2024-04-09 02:00:49